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Browsing by Author "Ozgurel, Banu"

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    Citation - WoS: 15
    Citation - Scopus: 14
    Analysis of the learning curve for robotic hysterectomy for benign gynaecological disease
    (John Wiley and Sons Ltd, 2014) Fatih Şendaǧ; Burak Zeybek; Ali Osman Akdemir; Banu Ozgurel; Kemal Öztekin; Akdemir, Ali; Ozgurel, Banu; Oztekin, Kemal; Zeybek, Burak; Sendag, Fatih
    Background: The objective was to evaluate the learning curve for performing a robotic hysterectomy to treat benign gynaecological disease. Methods: Thirty-six patients underwent robotic hysterectomy for benign indications. A systematic chart review of consecutive cases was conducted. The collected data included age BMI operating time set-up time docking time uterine weight blood loss intraoperative complications postoperative complications conversions to laparotomy and length of hospital stay. Results: The mean operating set-up and docking times were 169±54.5 52.9±12.4 and 7.8±7.6min respectively. The learning curve analysis revealed a decrease in both docking and operating times with both curves plateauing after case 9. Conclusions: The learning curve analysis revealed a decrease in docking time and operating time after case 9 suggesting that there might be a fast learning curve for experienced laparoscopic surgeons to master robotic hysterectomy and that the docking process does not have a significant negative influence on the overall operating time. © 2022 Elsevier B.V. All rights reserved.
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    Citation - WoS: 18
    Citation - Scopus: 19
    Learning Curve Analysis of Intracorporeal Cuff Suturing During Robotic Single-Site Total Hysterectomy
    (ELSEVIER SCIENCE INC, 2015) Ali Akdemir; Burak Zeybek; Banu Ozgurel; Mehmet Kemal Oztekin; Fatih Sendag; Akdemir, Ali; Ozgurel, Banu; Zeybek, Burak; Oztekin, Mehmet Kemal; Sendag, Fatih
    Study Objective: To analyze the learning curve of intracorporeal cuff suturing during robotic single-site total hysterectomy. Design: Retrospective study (Canadian Task Force classification Setting: University hospital. Patients: Twenty-four patients with benign indications for hysterectomy. Interventions: Twenty-four patients who underwent robotic single-site total hysterectomy to treat benign indications were included in the study. Surgical procedures were performed by a single surgeon with extensive experience in laparoscopy using the single-site platform of the da Vinci Surgical System. All vaginal cuffs were closed intracorporeally using semi-rigid single-site instruments. Measurements and Main Results: An exponential learning curve technique was used to analyze the learning curve. The overall mean (SD) vaginal cuff closure time was 23.2 (7) minutes. Learning curve analysis revealed a decrease in vaginal closure time after 14 procedures. Conclusions: An experienced robotic surgeon requires approximately 14 procedures to achieve proficiency in intracorporeal cuff suturing during robotic single-site total hysterectomy. Novel instruments that create perfect triangulation are needed to overcome the current challenges of suturing and to shorten operative time. (C) 2015 AAGL. All rights reserved.
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    Citation - WoS: 4
    Citation - Scopus: 5
    The Impact of Carbon Dioxide Pneumoperitoneum on Ovarian Ischemia-Reperfusion Injury during Laparoscopic Surgery: A Preliminary Study
    (ELSEVIER SCIENCE INC, 2018) Ali Akdemir; Enes Taylan; Cagdas Sahin; Banu Ozgurel; Ayfer Karlitepe; Osman Zekioglu; Gulinnaz Ercan; Taylan, Enes; Sahin, Cagdas; Karlitepe, Ayfer; Ercan, Gulinnaz; Akdemir, Ali; Zekioglu, Osman; Ozgurel, Banu
    Study Objective: To investigate whether carbon dioxide pneumoperitoneum causes ischemia-reperfusion injury to the ovaries during laparoscopic surgery. Design: A prospective controlled clinical study (Canadian Task Force classification II-1). Setting: A tertiary academic center. Patients: Premenopausal women who underwent hysterectomy with bilateral salpingo-oophorectomy (HSO) via open abdominal and laparoscopic approaches between 2014 and 2015. Interventions: In both surgical approaches unilateral oophorectomy was performed immediately after abdominal entry and the remaining contralateral ovary was excised at the end of the hysterectomy in order to compare the effect of these surgical procedures on ovarian tissue. Additionally plasma samples were collected at the following time points: (1) before abdominal entry (2) at the end of hysterectomy and (3) before contralateral oophorectomy. Plasma samples were assessed for biochemical oxidative stress markers malondialdehyde (MDA) and 8-hydroxy-2'-deoxyguanosine (8-OHdG). Ovarian tissue samples were assessed for MDA and further evaluated for ischemia-reperfusion injury using a histologic scoring method. Measurements and Main Results: Twenty premenopausal women undergoing HSO via open abdominal surgery (n = 10) and laparoscopy (n = 10) were included. Baseline characteristics (age body mass index parity and gravida) and operative data (operative time estimated blood loss and intraoperative complication) were similar between groups. Perioperative plasma MDA levels histologic scores and tissue oxidative stress markers did not show a significant difference in either group or between groups. However plasma 8-OHdG levels were significantly different when the second sample in the abdominal HSO group was compared with the first sample in the abdominal HSO group and the third sample in the laparoscopic HSO group (p =.012 and .001 respectively). Conclusion: Carbon dioxide pneumoperitoneum does not cause ischemia-reperfusion injury in the human ovaries at clinically safe levels of intra-abdominal pressure. (C) 2017 AAGL. All rights reserved.
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    Citation - WoS: 20
    Citation - Scopus: 23
    The impact of salpingectomy and single-dose systemic methotrexate treatments on ovarian reserve in ectopic pregnancy
    (ELSEVIER SCIENCE BV, 2016) Cagdas Sahin; Enes Taylan; Ali Akdemir; Banu Ozgurel; Dilek Taskiran; Ahmet M. Ergenoglu; Akdemir, Ali; Ergenoglu, Ahmet M.; Ozgurel, Banu; Taylan, Enes; Taskiran, Dilek; Sahin, Cagdas
    Objective: To investigate the effects of salpingectomy and methotrexate treatments on ovarian reserve in ectopic pregnancy. Study design: In this prospective study a total of 131 patients with ectopic pregnancy were divided into 3 groups of methotrexate (MTX) only (Group-1 n: 55) salpingectomy only (Group-2 n: 61) and salpingectomy following MTX (Group-3 n: 15). Pretreatment and post-treatment anti-Mullerian hormone (AMH) levels were evaluated. Results: Significant differences in AMH levels were detected between group 1 and group 2 (2.52 +/- 1.28 vs. 1.96 +/- 1.66 p = 0.043) and group 1 and group 3 (2.52 +/- 1.28 vs. 1.77 +/- 0.76 p = 0.035) at one month postoperative. However these differences disappeared at the 3rd postoperative month. When AMH levels were compared within the same group postoperative one month AMH levels were significantly lower than the preoperative AMH levels only in group 3 (p = 0.03). However this difference also disappeared at the 3rd postoperative month. Conclusion: Systemic single-dose methotrexate treatment unilateral salpingectomy and salpingectomy following methotrexate administration in ectopic pregnancy were reassuring based on pretreatment and post-treatment AMH levels. Current medical and surgical treatment approaches do not have an obvious negative effect on ovarian reserve. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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    Citation - WoS: 11
    Citation - Scopus: 15
    Which Should Be the Preferred Technique during Laparoscopic Ovarian Cystectomy: Hemostatic Sutures or Bipolar Electrocoagulation? A Randomized Controlled Prospective Study of Long-Term Ovarian Reserve
    (SAGE Publications Inc. claims@sagepub.com, 2017) Cagdas Sahin; Ali Osman Akdemir; Ahmet Mete Ergenoǧlu; Banu Ozgurel; Ahmet Özgür Yeniel; Dilek Taşkiran; Fatih Şendaǧ; Ergenoglu, Ahmet Mete; Sahin, Cagdas; Akdemir, Ali; Yeniel, Ahmet Ozgur; Ozgurel, Banu; Taskiran, Dilek; Sendag, Fatih
    The aim of the present study was to determine the long-term effects of different laparoscopic hemostatic techniques on ovarian reserve after ovarian cystectomy. Ninety patients with unilateral ovarian cysts were recruited and randomly distributed into 2 groups. Laparoscopic stripping cystectomy was performed in all patients. Afterward cystectomy hemostasis was achieved via hemostatic suture or bipolar electrocoagulation. Serum levels of anti-Müllerian hormone (AMH) were determined preoperatively and postoperatively at 1 3 and 12 months and patients were evaluated for residual ovarian volume antral follicle count and pregnancy. The statistical difference was determined between the 2 groups in terms of AMH levels at 3 months (hemostatic suture group = 3.17 ± 3.40 vs bipolar electrocoagulation group = 2.38 ± 2.57 P =.006) and 12 months (hemostatic suture group = 3.71 ± 3.09 vs bipolar electrocoagulation group = 2.78 ± 2.85 P =.005). In addition in the hemostatic suture group there was no statistically significant difference between preoperative and postoperative AMH levels (P =.165) and between the postoperative antral follicle count (P =.779) and the residual ovarian volume (P =.248) whereas in the bipolar electrocoagulation group postoperative AMH levels were lower than preoperative levels (P =.028) and postoperative residual ovarian volumes at 3 and 12 months were lower than those at 1 month (P =.001). Nonetheless pregnancy rates were not significantly different (P =.546). Bipolar electrocoagulation is more destructive compared with hemostatic suture. However the ovarian reserve does not decrease further during the follow-up period. © 2017 Elsevier B.V. All rights reserved.
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