Browsing by Author "Sinci, Kazim Ayberk"

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    Citation - WoS: 4
    Citation - Scopus: 3
    Deep learning-based classification of parotid gland tumors: integrating dynamic contrast-enhanced MRI for enhanced diagnostic accuracy
    (BMC, 2025) Kazim Ayberk Sinci; Ilker Ozgur Koska; Yusuf Kenan Cetinoglu; Nezahat Erdogan; Ali Murat Koc; Nuket Ozkavruk Eliyatkin; Cagan Koska; Barkan Candan; Erdogan, Nezahat; Sinci, Kazim Ayberk; Koska, Ilker Ozgur; Koc, Ali Murat; Cetinoglu, Yusuf Kenan; Eliyatkin, Nuket Ozkavruk; Candan, Barkan
    BackgroundTo evaluate the performance of deep learning models in classifying parotid gland tumors using T2-weighted diffusion-weighted and contrast-enhanced T1-weighted MR images along with DCE data derived from time-intensity curves.MethodsIn this retrospective single-center study including a total of 164 participants 124 patients with surgically confirmed parotid gland tumors and 40 individuals with normal parotid glands underwent multiparametric MRI including DCE sequences. Data partitions were performed at the patient level (80% training 10% validation 10% testing). Two deep learning architectures (MobileNetV2 and EfficientNetB0) as well as a combined approach integrating predictions from both models were fine-tuned using transfer learning to classify (i) normal versus tumor (Task 1) (ii) benign versus malignant tumors (Task 2) and (iii) benign subtypes (Warthin tumor vs. pleomorphic adenoma) (Task 3). For Tasks 2 and 3 DCE-derived metrics were integrated via a support vector machine. Classification performance was assessed using accuracy precision recall and F1-score with 95% confidence intervals derived via bootstrap resampling.ResultsIn Task 1 EfficientNetB0 achieved the highest accuracy (85%). In Task 2 the combined approach reached an accuracy of 65% while adding DCE data significantly improved performance with MobileNetV2 achieving an accuracy of 96%. In Task 3 EfficientNetB0 demonstrated the highest accuracy without DCE data (75%) while including DCE data boosted the combined approach to an accuracy of 89%.ConclusionsAdding DCE-MRI data to deep learning models substantially enhances parotid gland tumor classification accuracy highlighting the value of functional imaging biomarkers in improving noninvasive diagnostic workflows.