PubMed İndeksli Yayınlar Koleksiyonu
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Browsing PubMed İndeksli Yayınlar Koleksiyonu by Publisher "Elsevier B.V."
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Article Fiscal responses to COVID-19 outbreak for healthy economies: Modelling with big data analytics(Elsevier B.V., 2023-03) Gorkem Sariyer; Serpil Kahraman; Mert Erkan Sözen; Mustafa Gökalp AtamanFiscal responses to the COVID-19 crisis have varied a lot across countries. Using a panel of 127 countries over two separate subperiods between 2020 and 2021 this paper seeks to determine the extent that fiscal responses contributed to the spread and containment of the disease. The study first documents that rich countries which had the largest total and health-related fiscal responses achieved the lowest fatality rates defined as the ratio of COVID-related deaths to cases despite having the largest recorded numbers of cases and fatalities. The next most successful were less developed economies whose smaller total fiscal responses included a larger health-related component than emerging market economies. The study used a promising big data analytics technology the random forest algorithm to determine which factors explained a country's fatality rate. The findings indicate that a country's fatality ratio over the next period can be almost entirely predicted by its economic development level fiscal expenditure (both total and health-related) and initial fatality ratio. Finally the study conducted a counterfactual exercise to show that had less developed economies implemented the same fiscal responses as the rich (as a share of GDP) then their fatality ratios would have declined by 20.47% over the first period and 2.59% over the second one. © 2023 Elsevier B.V. All rights reserved.Article Learning Curve Analysis of Intracorporeal Cuff Suturing During Robotic Single-Site Total Hysterectomy(Elsevier B.V., 2015-03) Ali Osman Akdemir; Burak Zeybek; Banu Ozgurel; Mehmet Kemal Öztekin; Fatih ŞendaǧStudy Objective: To analyze the learning curve of intracorporeal cuff suturing during robotic single-site total hysterectomy. Design: Retrospective study (Canadian Task Force classification II-1). Setting: University hospital. Patients: Twenty-four patients with benign indications for hysterectomy. Interventions: Twenty-four patients who underwent robotic single-site total hysterectomy to treat benign indications were included in the study. Surgical procedures were performed by a single surgeon with extensive experience in laparoscopy using the single-site platform of the da Vinci Surgical System. All vaginal cuffs were closed intracorporeally using semi-rigid single-site instruments. Measurements and Main Results: An exponential learning curve technique was used to analyze the learning curve. The overall mean (SD) vaginal cuff closure time was 23.2 (7) minutes. Learning curve analysis revealed a decrease in vaginal closure time after 14 procedures. Conclusions: An experienced robotic surgeon requires approximately 14 procedures to achieve proficiency in intracorporeal cuff suturing during robotic single-site total hysterectomy. Novel instruments that create perfect triangulation are needed to overcome the current challenges of suturing and to shorten operative time. © 2021 Elsevier B.V. All rights reserved.Article Citation - Scopus: 3Reflection predicts and leads to decreased conspiracy belief(Elsevier B.V., 2025-05) Fatih Bayrak; Vahdet Sümer; Burak Doǧruyol; Selahattin Adil Saribay; Sinan Alper; Ozan Isler; Onurcan Yilmaz; Sümer, Vahdet; Saribay, S. Adil; Isler, Ozan; Dogruyol, Burak; Alper, Sinan; Yilmaz, Onurcan; Bayrak, FatihRecent research indicates a generally negative relationship between reflection and conspiracy beliefs. However most of the existing research relies on correlational data on WEIRD (Western Educated Industrialized Rich Democratic) populations. The few existing experimental studies are limited by weak manipulation techniques that fail to reliably activate cognitive reflection. Hence questions remain regarding (1) the consistency of the negative relationship between conspiracy beliefs and cognitive reflection (2) the extent of cross-cultural variation and potential moderating factors and (3) the presence of a causal link between cognitive reflection and conspiracy beliefs. In two preregistered studies we investigated the association between cognitive reflection and conspiracy beliefs. First we studied the correlation between two variables across 48 cultures and investigated whether factors such as WEIRDness and narcissism (personal and collective) moderate this relationship. In the second study we tested the causal effect of reflection using a reliable and effective manipulation technique—debiasing training—on both generic and specific conspiracy beliefs. The first study confirmed the negative association between reflection and belief in conspiracy theories across cultures with the association being notably stronger in non-WEIRD societies. Both personal and collective narcissism played significant moderating roles. The second study demonstrated that debiasing training significantly decreases both generic and COVID-19 conspiracy beliefs in a non-WEIRD context with more pronounced effects for general conspiracy beliefs. Our research supports that reflection is a consistent cross-cultural predictor of conspiracy beliefs and that activating reflection can reduce such beliefs through rigorous experimental interventions. © 2025 Elsevier B.V. All rights reserved.Article The Impact of Carbon Dioxide Pneumoperitoneum on Ovarian Ischemia-Reperfusion Injury during Laparoscopic Surgery: A Preliminary Study(Elsevier B.V., 2018-05) Ali Osman Akdemir; Enes Taylan; Cagdas Sahin; Banu Ozgurel; Ayfer Karlitepe; Osman Zekioǧlu; Gülinnaz Alper ErcanStudy Objective: To investigate whether carbon dioxide pneumoperitoneum causes ischemia-reperfusion injury to the ovaries during laparoscopic surgery. Design: A prospective controlled clinical study (Canadian Task Force classification II-1). Setting: A tertiary academic center. Patients: Premenopausal women who underwent hysterectomy with bilateral salpingo-oophorectomy (HSO) via open abdominal and laparoscopic approaches between 2014 and 2015. Interventions: In both surgical approaches unilateral oophorectomy was performed immediately after abdominal entry and the remaining contralateral ovary was excised at the end of the hysterectomy in order to compare the effect of these surgical procedures on ovarian tissue. Additionally plasma samples were collected at the following time points: (1) before abdominal entry (2) at the end of hysterectomy and (3) before contralateral oophorectomy. Plasma samples were assessed for biochemical oxidative stress markers malondialdehyde (MDA) and 8-hydroxy-2’-deoxyguanosine (8-OHdG). Ovarian tissue samples were assessed for MDA and further evaluated for ischemia-reperfusion injury using a histologic scoring method. Measurements and Main Results: Twenty premenopausal women undergoing HSO via open abdominal surgery (n = 10) and laparoscopy (n = 10) were included. Baseline characteristics (age body mass index parity and gravida) and operative data (operative time estimated blood loss and intraoperative complication) were similar between groups. Perioperative plasma MDA levels histologic scores and tissue oxidative stress markers did not show a significant difference in either group or between groups. However plasma 8-OHdG levels were significantly different when the second sample in the abdominal HSO group was compared with the first sample in the abdominal HSO group and the third sample in the laparoscopic HSO group (p =.012 and.001 respectively). Conclusion: Carbon dioxide pneumoperitoneum does not cause ischemia-reperfusion injury in the human ovaries at clinically safe levels of intra-abdominal pressure. © 2019 Elsevier B.V. All rights reserved.

