PubMed İndeksli Yayınlar Koleksiyonu

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Now showing 1 - 13 of 13

Citation - WoS: 20
Citation - Scopus: 26
An analysis of Emergency Medical Services demand: Time of day- day of the week- and location in the city
(ELSEVIER, 2017-06) Gorkem Sariyer; Mustafa Gokalp Ataman; Serhat Akay; Turhan Sofuoglu; Zeynep Sofuoglu; Ataman, Mustafa Gokalp; Sariyer, Gorkem; Sofuoglu, Turhan; Akay, Serhat; Sofuoglu, Zeynep
Objective: Effective planning of Emergency Medical Services (EMS) which is highly dependent on the analysis of past data trends is important in reducing response time. Thus we aimed to analyze demand for these services based on time and location trends to inform planning for an effective EMS. Materials and methods: Data for this retrospective study were obtained from the Izmir EMS 112 system. All calls reaching these services during first six months of 2013 were descriptively analyzed based on time and location trends as a heat-map form. Results: The analyses showed that demand for EMS varied within different time periods of day and according to day of the week. For the night period demand was higher at the weekend compared to weekdays whereas for daytime hours demand was higher during the week. For weekdays a statistically significant relation was observed between the call distribution of morning and evening periods. It was also observed that the percentage of demand changed according to location. Among 30 locations the five most frequent destinations for ambulances which are also correlated with high population densities accounted for 55.66% of the total. Conclusion: The results of this study shed valuable light on the areas of call center planning and optimal ambulance locations of Izmir which can also be served as an archetype for other cities. Copyright (C) 2016 The Emergency Medicine Association of Turkey. Production and hosting by Elsevier B.V. on behalf of the Owner. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Citation - WoS: 6
Citation - Scopus: 7
Bifurcation analysis of bistable and oscillatory dynamics in biological networks using the root-locus method
(INST ENGINEERING TECHNOLOGY-IET, 2019-12) Neslihan Avcu; Cuneyt Guzelis; Guzelis, Cuneyt; Avcu, Neslihan
Most of the biological systems including gene regulatory networks can be described well by ordinary differential equation models with rational non-linearities. These models are derived either based on the reaction kinetics or by curve fitting to experimental data. This study demonstrates the applicability of the root-locus-based bifurcation analysis method for studying the complex dynamics of such models. The effectiveness of the bifurcation analysis in determining the exact parameter regions in each of which the system shows a certain dynamical behaviour such as bistability oscillation and asymptotically equilibrium dynamics is shown by considering two mostly studied gene regulatory networks namely Gardner's genetic toggle switch and p53 gene network possessing two-phase (mono-stable/oscillation) dynamics.
Citation - WoS: 6
Citation - Scopus: 6
Child Abuse and Neglect Among Children Who Drop Out of School: A Study in Izmir- Turkey
(ROUTLEDGE JOURNALS TAYLOR & FRANCIS LTD, 2016-06-22) Zeynep Sofuoglu; Gorkem Sariyer; Fulya Aydin; Sinem Cankardas; Birsu Kandemirci; Sariyer, Görkem; Aydin, Fulya; Cankardeş, Sinem; Cankardas, Sinem; Sofuoğlu, Zeynep; Kandemirci, Birsu
Child abuse and neglect (CAN) and dropping out of school have long been recognized as pervasive social problems globally and Turkey is no exception. This study aims to explore the prevalence and incidence of CAN in children who drop out of school of Turkey using the ISPCAN Child abuse Screening Tool Children's Version which is an appropriate tool for multinational comparisons. Data from a convenience sample of children who drop out of school age 11 13 and 16 from Izmir were collected either by interviews or by self-completion. The results show that compared to children who do not drop out of school children who drop out of school have higher rates of psychological and physical abuse and neglect within the family. This study not only highlights the need for preventive laws for CAN and dropping out of school but also points to direction for future research.
Citation - WoS: 26
Citation - Scopus: 25
Compensatory usage of the internet: The case of mukbang watching on youtube
(Korean Neuropsychiatric Association, 2021-04-25) Kağan Kircaburun; Sabah Balta; Emrah Emirtekin; Şule Betül Tosuntaş; Zsolt Demetrovics; Mark D. Griffiths; Kircaburun, Kagan; Emirtekin, Emrah; Balta, Sabah; Tosuntaş, Şule Betül; Demetrovics, Zsolt; Griffiths, Mark D.
Objective Accumulating empirical research has emphasized that a wide range of online activities–such as using social networking sites–can be performed in order to compensate unattained needs or to cope with negative affect and psychopathological symptoms. Al-though the correlates of problematic social networking use have been extensively investigated less is known about problematic YouTube use (PYU) an umbrella term grouping a number of different activities (e.g. viewing of online video games watching specific YouTube channels). Furthermore nothing is known concerning increasingly popular and distinct YouTube-related activities such as mukbang watching (i.e. watching livestream “eating broadcasts” where someone eats various foods in front of the camera while interacting with viewers). The aim of the present study was to examine the mediating role of problematic mukbang watching (PMW) on the relationships between depression and loneliness with PYU. Methods An online survey that comprised assessment tools for aforementioned variables was administered to 217 mukbang viewers (mean age=20.58 years range 18–33 years). Results Results indicated that PMW was positively related to loneliness and PYU. Depression was positively and directly associated with PYU but was not associated with PMW. Conclusion Further research is required to better understand the psychological processes underlying problematic mukbang watching and its association with other mental health conditions (e.g. addictive disorders eating disorders). © 2021 Elsevier B.V. All rights reserved.
Citation - WoS: 1
Citation - Scopus: 1
Coupling of cell fate selection model enhances DNA damage response and may underlie BE phenomenon
(INST ENGINEERING TECHNOLOGY-IET, 2020-04) Goekhan Demirkiran; Guleser Kalayc Demir; Cuneyt Guzelis; Guzelis, Cuneyt; Demirkiran, Goekhan; Demir, Guleser Kalayci
Double-strand break-induced (DSB) cells send signal that induces DSBs in neighbour cells resulting in the interaction among cells sharing the same medium. Since p53 network gives oscillatory response to DSBs such interaction among cells could be modelled as an excitatory coupling of p53 network oscillators. This study proposes a plausible coupling model of three-mode two-dimensional oscillators which models the p53-mediated cell fate selection in globally coupled DSB-induced cells. The coupled model consists of ATM and Wip1 proteins as variables. The coupling mechanism is realised through ATM variable via a mean-field modelling the bystander signal in the intercellular medium. Investigation of the model reveals that the coupling generates more sensitive DNA damage response by affecting cell fate selection. Additionally the authors search for the cause-effect relationship between coupled p53 network oscillators and bystander effect (BE) endpoints. For this they search for the possible values of uncertain parameters that may replicate BE experiments' results. At certain parametric regions there is a correlation between the outcomes of cell fate and endpoints of BE suggesting that the intercellular coupling of p53 network may manifest itself as the form of observed BEs.
Citation - WoS: 43
Citation - Scopus: 48
Decision tree (DT) generalized regression neural network (GR) and multivariate adaptive regression splines (MARS) models for sediment transport in sewer pipes
(IWA Publishing 12 Caxton Street London SW1H 0QS, 2019-03-15) Mir Jafar Sadegh Safari; Safari, Mir Jafar Sadegh
Sediment deposition in sewers and urban drainage systems has great effect on the hydraulic capacity of the channel. In this respect the self-cleansing concept has been widely used for sewers and urban drainage systems design. This study investigates the bed load sediment transport in sewer pipes with particular reference to the non-deposition condition in clean bed channels. Four data sets available in the literature covering wide ranges of pipe size sediment size and sediment volumetric concentration have been utilized through applying decision tree (DT) generalized regression neural network (GR) and multivariate adaptive regression splines (MARS) techniques for modeling. The developed models have been compared with conventional regression models available in the literature. The model performance indicators showed that DT GR and MARS models outperform conventional regression models. Result shows that GR and MARS models are comparable in terms of calculating particle Froude number and performing better than DT. It is concluded that conventional regression models generally overestimate particle Froude number for the non-deposition condition of sediment transport while DT GR and MARS outputs are close to their measured counterparts. © 2019 Elsevier B.V. All rights reserved.
Encoding-Stage Adaptation Effects: Long-Term Memory
(SAGE Publications Ltd, 2017-11-10) Candace E. Peacock; Filiz Gözenman
Given adaptation changes perceptual experience it probably shapes long-term memory (LTM). Across four experiments participants were adapted to strongly gendered (male female: Experiments 1 and 2) or aged faces (old young: Experiments 3 and 4) before LTM encoding and later completed an LTM test in which the encoded faces were morphed with the opposite end of the relevant continuum. At retrieval participants judged whether probe faces were more or less male or female or young or old than when presented during encoding. For male female and young faces encoding-stage adaptation significantly shifted the point of subjective equality in the unadapted direction. Additionally encoding-stage adaptation significantly enhanced recognition of faces during LTM retrieval. We conclude that encoding-related adaptation is reflected in LTM. © 2022 Elsevier B.V. All rights reserved.
Citation - WoS: 11
Citation - Scopus: 10
Factors Relating to Decision Delay in the Emergency Department: Effects of Diagnostic Tests and Consultations
(Dove Medical Press Ltd, 2023-04) Mustafa Gökalp Ataman; Gorkem Sariyer; Caner Saǧlam; Arif Karagöz; Erden Erol Ünlüer; Ataman, Mustafa Gokalp; Sariyer, Gorkem; Karagoz, Arif; Unluer, Erden Erol; Saglam, Caner
Purpose: The purpose of this study is to investigate the factors increasing waiting time (WT) and length of stay (LOS) in patients which may cause delays in decision-making in the emergency departments (ED). Patients and Methods: Patients who arrived at a training hospital in the central region of Izmir City Turkey during the first quarter of 2020 were retrospectively analyzed. WT and LOS were the outcome variables of the study and gender age arrival type triage level determined based on the clinical acuity diagnosis encoded based on International Classification of Diseases-10 (ICD-10) the existence of diagnostic tests or consultation status were the identified factors. The significance of the differences in WT and LOS values based on each level of these factors was analyzed using independent sample t-tests and ANOVA. Results: While patients for which no diagnostic testing or consultation was requested had a significantly higher WT in EDs their LOS values were substantially lower than those for which at least one diagnostic test or consultation was ordered (p≤0.001). Besides elderly and red zone patients and those who arrived by ambulance had significantly lower WT and higher LOS values than other levels for all groups of patients for which laboratory-type or imaging-type diagnostic test or consultation was requested (p≤0.001 for each comparison). Conclusion: Besides ordering diagnostic tests or consultation in EDs different factors may extend patients’ WT and LOS values and cause significant decision-making delays. Understanding the patient characteristics associated with longer waiting times and LOS values and thus delayed decisions will enable practitioners to improve operations management in EDs. © 2023 Elsevier B.V. All rights reserved.
Learning Curve Analysis of Intracorporeal Cuff Suturing During Robotic Single-Site Total Hysterectomy
(Elsevier B.V., 2015-03) Ali Osman Akdemir; Burak Zeybek; Banu Ozgurel; Mehmet Kemal Öztekin; Fatih Şendaǧ
Study Objective: To analyze the learning curve of intracorporeal cuff suturing during robotic single-site total hysterectomy. Design: Retrospective study (Canadian Task Force classification II-1). Setting: University hospital. Patients: Twenty-four patients with benign indications for hysterectomy. Interventions: Twenty-four patients who underwent robotic single-site total hysterectomy to treat benign indications were included in the study. Surgical procedures were performed by a single surgeon with extensive experience in laparoscopy using the single-site platform of the da Vinci Surgical System. All vaginal cuffs were closed intracorporeally using semi-rigid single-site instruments. Measurements and Main Results: An exponential learning curve technique was used to analyze the learning curve. The overall mean (SD) vaginal cuff closure time was 23.2 (7) minutes. Learning curve analysis revealed a decrease in vaginal closure time after 14 procedures. Conclusions: An experienced robotic surgeon requires approximately 14 procedures to achieve proficiency in intracorporeal cuff suturing during robotic single-site total hysterectomy. Novel instruments that create perfect triangulation are needed to overcome the current challenges of suturing and to shorten operative time. © 2021 Elsevier B.V. All rights reserved.
Practice-induced SNARC: evidence from a null-SNARC sample
(Springer Science and Business Media Deutschland GmbH, 2024-05-13) Ezgi Palaz; Hakan Çetinkaya; Zeynep Tuncali; Bengi Kamar; Seda Dural
The mental representation of numbers inherently involves a spatial organization often positioning smaller numbers to the left and larger numbers to the right. The SNARC effect characterized by faster responses to small numbers using the left hand and vice versa for large numbers is typically attributed to this left-to-right oriented mental number line (MNL). However the direction of the SNARC effect seems to rely on reading direction with most research exploring these mechanisms conducted within left-to-right reading cultures where the SNARC effect is prevalent. This study takes advantage of a sample from a left-to-right reading culture that does not exhibit the SNARC effect allowing us to isolate and elucidate the stand-alone effects of recent experiences on SNARC. Therefore the current study aims to investigate how MNL-compatible and MNL-incompatible practices induce an effect within a sample lacking the SNARC effect. To accomplish this we reinvited the individuals from the sample which had previously shown no SNARC and retested those who agreed to take part in the current study after an MNL-compatible or MNL-incompatible practice manipulation. The findings revealed an absence of the SNARC effect with MNL-compatible practices. Conversely MNL-incompatible practices yielded a reverse SNARC effect. These results prompt a discussion on SNARC mechanisms within the framework of practice effects. © 2024 Elsevier B.V. All rights reserved.
Representational Context Modulates the Direction and Transiency of Practice Effects on SNARC
(SAGE Publications Ltd, 2025-09-30) Palaz, Ezgi; Cetinkaya, Hakan; Dural, Seda
The Spatial-Numerical Association of Response Codes (SNARC) effect typically results in faster left-hand responses for small numbers and right-hand responses for large numbers, aligning with the concept of the mental number line (MNL). It is a robust but a flexible phenomenon that can reverse direction depending on the spatial-numerical mappings employed. This study investigates the potential modulatory effects of two contrasting representational contexts (ruler vs. clockface) on the emergence and persistence of the SNARC effect under two opposing spatial-numerical practices (MNL-compatible vs. MNL-incompatible). In Experiment 1, a magnitude classification task was employed as a practice session including either MNL-compatible or MNL-incompatible stimulus-response mappings, and the transfer and transiency of practice effects were examined by engaging participants in three test parity judgment tasks administered 5 min, 1 day, and 1 week after the practice session. In Experiment 2, different representational contexts were introduced during practice sessions. Experiment 2a utilized an image of a ruler as the context consistent with the MNL, while Experiment 2b employed a clockface image as an inconsistent context. Participants underwent testing three times to assess changes in performance over time. Results revealed that MNL-compatible practice effects did not transfer while MNL-incompatible practice effects resulted in a reverse SNARC effect persisting for up to 1 day. However, introducing the ruler context eliminated this transfer, while the clockface context reduced the persistence of the practice effect.
The Impact of Carbon Dioxide Pneumoperitoneum on Ovarian Ischemia-Reperfusion Injury during Laparoscopic Surgery: A Preliminary Study
(Elsevier B.V., 2018-05) Ali Osman Akdemir; Enes Taylan; Cagdas Sahin; Banu Ozgurel; Ayfer Karlitepe; Osman Zekioǧlu; Gülinnaz Alper Ercan
Study Objective: To investigate whether carbon dioxide pneumoperitoneum causes ischemia-reperfusion injury to the ovaries during laparoscopic surgery. Design: A prospective controlled clinical study (Canadian Task Force classification II-1). Setting: A tertiary academic center. Patients: Premenopausal women who underwent hysterectomy with bilateral salpingo-oophorectomy (HSO) via open abdominal and laparoscopic approaches between 2014 and 2015. Interventions: In both surgical approaches unilateral oophorectomy was performed immediately after abdominal entry and the remaining contralateral ovary was excised at the end of the hysterectomy in order to compare the effect of these surgical procedures on ovarian tissue. Additionally plasma samples were collected at the following time points: (1) before abdominal entry (2) at the end of hysterectomy and (3) before contralateral oophorectomy. Plasma samples were assessed for biochemical oxidative stress markers malondialdehyde (MDA) and 8-hydroxy-2’-deoxyguanosine (8-OHdG). Ovarian tissue samples were assessed for MDA and further evaluated for ischemia-reperfusion injury using a histologic scoring method. Measurements and Main Results: Twenty premenopausal women undergoing HSO via open abdominal surgery (n = 10) and laparoscopy (n = 10) were included. Baseline characteristics (age body mass index parity and gravida) and operative data (operative time estimated blood loss and intraoperative complication) were similar between groups. Perioperative plasma MDA levels histologic scores and tissue oxidative stress markers did not show a significant difference in either group or between groups. However plasma 8-OHdG levels were significantly different when the second sample in the abdominal HSO group was compared with the first sample in the abdominal HSO group and the third sample in the laparoscopic HSO group (p =.012 and.001 respectively). Conclusion: Carbon dioxide pneumoperitoneum does not cause ischemia-reperfusion injury in the human ovaries at clinically safe levels of intra-abdominal pressure. © 2019 Elsevier B.V. All rights reserved.
Citation - WoS: 1
Citation - Scopus: 1
The Impact of Socioeconomic Factors on the HIV-Related Stigma of People Living With HIV in Turkey
(SAGE PUBLICATIONS INC, 2025-04-11) Hulya Ozkan Ozdemir; Fatma Nur Karaman Kabadurmus; Durmus Ozdemir; Özdemir, Hülya Özkan; Karaman Kabadurmuş, Fatma Nur; Özdemir, Durmuş; Kabadurmus, Fatma Nur Karaman
This study includes clinical cohort data on 202 People Living with HIV/AIDS (PLWHA) in Izmir Turkey. Study is conducted at the Izmir Bozyaka Education and Training Hospital Department of Infectious Diseases and Clinical Microbiology and analyzes the impact of demographic socio-economic and clinical factors of HIV stigma which includes three dimensions of stigma: internalized anticipated and enacted. This paper uses clinic data recorded by patients and healthcare professionals of the outpatient clinic. In order to obtain socio-economic measures patients were interviewed face-to-face. We employ a logistics regression model that aligns with our binary stigma variables. Robustness checks include Ordinary Least Squares and Ordered Logistics models. Our results show that age and marital status are the 2 important demographic factors that affect stigmatized attitudes. Divorced PLWHA have a higher degree of both internalized and anticipated stigma. We find that educated people have a lower degree of internalized stigma. In addition a higher-income level is found to be inversely associated with enacted stigma. Our results also reveal that LGBTs drug users and people who have chronic illnesses have experienced higher stigma levels. This paper explores the complex ways socioeconomic factors contribute to stigma in the Turkish context addressing a significant gap in the literature since the cultural and social dynamics of stigma in Turkey are frequently overlooked. Recognizing the protective influence of education and income policies such as integrating HIV education into school curricula and offering financial assistance to PLWHA especially those from low-income backgrounds can help reduce stigma.

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