Nurten YilmazFatih OzogulMehran MoradiEylem Ezgi FadıloğluVida ŠimatJ. M. RochaSimat, VidaMoradi, MehranRocha, Joao MiguelFadiloglu, Eylem EzgiOzogul, FatihYilmaz, Nurten2025-10-06202201681656, 187348630168-16561873-486310.1016/j.jbiotec.2022.09.0032-s2.0-85138422356https://www.scopus.com/inward/record.uri?eid=2-s2.0-85138422356&doi=10.1016%2Fj.jbiotec.2022.09.003&partnerID=40&md5=f3d6031143d82ecfe5c0393f49bc0030https://gcris.yasar.edu.tr/handle/123456789/8645https://doi.org/10.1016/j.jbiotec.2022.09.003Postbiotics is a novel term proposed to describe as a set of bioactive compounds obtained from beneficial microorganisms. In this work postbiotics from four lactic acid bacteria (LAB) including Leuconostoc mesenteroides subsp. cremoris Pediococcus acidilactici Lactococcus lactis subsp. lactis and Streptococcus thermophilus were prepared in MRS broth. The antimicrobial properties and organic acids content of postbiotics were also investigated. Postbiotics were used to tentatively reduce the production of biogenic amines by foodborne pathogens (i.e. Salmonella paratyphi A and Escherichia coli) on lysine decarboxylase broth (LDB). Experimental data showed that acetic propionic and butyric acids were in the range of 387.51–709.21 mg/L 0.00–1.28 mg/L and 0.00–20.98 mg/L respectively. The inhibition zone of postbiotics on E. coli and S. paratyphi A were 11.67 and 12.33 mm respectively. Two different levels of postbiotics (25% and 50%) were used in LDB to measure the diamines (cadaverine and putrescine) polyamines (agmatine spermidine and spermine ammonia) and other biogenic amine formation by pathogens. E. coli produced cadaverine and putrescine with concentrations of 1072.21 and 1114.18 mg/L respectively. The postbiotics reduced cadaverine formation by 67% in E. coli and cadaverine production was mostly suppressed by postbiotics from P. acidilactici in E. coli (97%) and L. lactis subsp. lactis in S. paratyphi A (90%). Putrescine production by E. coli was reduced by 94% with postbiotics of P. acidilactici at a concentration of 25% whereas putrescine production by S. paratyphi A has been decreased by 61% in the presence of postbiotics from L. lactis subsp. Lactis with a 25% concentration. The results revealed that an increase in postbiotics concentration (from 25% to 50%) in LDB may lead to synergistic effects resulting from the production of biogenic amines by microbial pathogens. It was importantly concluded that postbiotics of LAB may degrade biogenic amines or prevent their formation by foodborne pathogens. © 2023 Elsevier B.V. All rights reserved.Englishinfo:eu-repo/semantics/closedAccessBiogenic Amines, Cell-free Supernatant, Foodborne Pathogens, Lysine Decarboxylase Broth, Postbiotic Solution, Acetic Acid, Agmatine, Ammonia, Butyric Acid, Cadaverine, Lysine Decarboxylase, Propionic Acid, Putrescine, Spermidine, Spermine, Carboxylyase, Lysine, Agmatine, Ammonia, Biogenic Amines, Butyrates, Cadaverine, Carboxy-lyases, Lysine, Lysine Decarboxylase, Putrescine, Spermidine, Spermine, Amines, Amino Acids, Ammonia, Butyric Acid, Food Microbiology, Lactic Acid, Pathogens, Propionic Acid, Salmonella, Biogenic Amines, Cell-free, Cell-free Supernatant, Decarboxylases, E. Coli, Food-borne Pathogens, Lactic Acid Bacteria, Lysine Decarboxylase Broth, Postbiotic Solution, Supernatants, Escherichia Coli, Acetic Acid, Agmatine, Ammonia, Antibiotic Agent, Biogenic Amine, Butyric Acid, Cadaverine, Carboxylic Acid, Lysine Decarboxylase, Microbial Products Not Classified Elsewhere, Postbiotic Agent, Propionic Acid, Putrescine, Spermidine, Spermine, Unclassified Drug, Butyric Acid Derivative, Carboxylyase, Lysine, Antibacterial Activity, Antimicrobial Activity, Article, Concentration Response, Controlled Study, Foodborne Pathogen, Lactococcus Lactis Subsp. Lactis, Leuconostoc Mesenteroides, Nonhuman, Pediococcus Acidilactici, Ph, Reversed Phase High Performance Liquid Chromatography, Salmonella Enterica Serovar Paratyphi A, Streptococcus Thermophilus, Zone Of Inhibition, Lactococcus Lactis, Metabolism, Agmatine, Biogenic Amines, Butyrates, Cadaverine, Carboxy-lyases, Lysine, Putrescine, Spermidine, SpermineAmines, Amino acids, Ammonia, Butyric acid, Food microbiology, Lactic acid, Pathogens, Propionic acid, Salmonella, Biogenic amines, Cell-free, Cell-free supernatant, Decarboxylases, E. coli, Food-borne pathogens, Lactic acid bacteria, Lysine decarboxylase broth, Postbiotic solution, Supernatants, Escherichia coli, acetic acid, agmatine, ammonia, antibiotic agent, biogenic amine, butyric acid, cadaverine, carboxylic acid, lysine decarboxylase, microbial products not classified elsewhere, postbiotic agent, propionic acid, putrescine, spermidine, spermine, unclassified drug, butyric acid derivative, carboxylyase, lysine, antibacterial activity, antimicrobial activity, Article, concentration response, controlled study, foodborne pathogen, Lactococcus lactis subsp. lactis, Leuconostoc mesenteroides, nonhuman, Pediococcus acidilactici, pH, reversed phase high performance liquid chromatography, Salmonella enterica serovar Paratyphi A, Streptococcus thermophilus, zone of inhibition, Lactococcus lactis, metabolism, Agmatine, Biogenic Amines, Butyrates, Cadaverine, Carboxy-Lyases, Lysine, Putrescine, Spermidine, SpermineBiogenic AminesCell-Free SupernatantCell -Free SupernatantFoodborne PathogensPostbiotic SolutionLysine Decarboxylase BrothArticle