A comparison of feature selection algorithms for cancer classification through gene expression data: Leukemia case

Abstract

In this study three different feature selection algorithms are compared using Support Vector Machines as classifier for cancer classification through gene expression data. The ability of feature selection algorithms to select an optimal gene subset for a cancer type is evaluated by the classification ability of selected genes. A publicly available micro array dataset is employed for gene expression values. Selected gene subsets were able to classify subtypes of the considered cancer type with high accuracies and showed that these feature selection methods were applicable for bio-marker gene selection. © 2023 Elsevier B.V. All rights reserved.